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Senior research assistant, mrna manufacture

Brisbane
The University Of Queensland
Posted: 15 June
Offer description

About This Opportunity

BASE Facility, based in the Australian Institute for Bioengineering and Nanotechnology (AIBN) Full‐time (100%), fixed‐term position for up to 12 months. Base salary will be in the range $85,451.97 - $94,983.84 + 17% super (HEW Level 5). Based at our Translational Research Institute site in Woolloongabba.

Join the innovative and collaborative BASE Facility team as Senior Research Assistant to provide technical research support and subject matter expertise in support of mRNA manufacturing. You will be responsible for supporting mRNA manufacturing operations and performing analytical methods to assess the quality and characteristics of mRNA products throughout the manufacturing process.

This position plays a crucial role in ensuring the production of high‐quality mRNA products within our cutting‐edge manufacturing facility.

Key Responsibilities
* Coordinate aspects of mRNA products manufacturing, including template synthesis, purification, IVT processes and formulation.
* Validate and execute analytical assays for the characterisation of mRNA quality attributes, including assays for purity, integrity, and stability.
* Assist in the design of optimisation studies, under supervision of senior staff to improve manufacturing processes for efficiency, yield, and quality.
* Maintain accurate and detailed records of experiments, procedures, and results.
* Generate and follow Standard Operating Procedures with a high attention to detail.
* Troubleshoot issues with manufacturing process/technical equipment, proposing and implementing solutions to ensure smooth operations under the guidance of supervisor.
* Undertake maintenance and upkeep of facilities and equipment.
* Contribute to the safe and efficient operation of research equipment, infrastructure, methodologies and protocols.
* Ensure the appropriate storage, handling and disposal of chemicals, equipment, stores and/or samples/specimens.
* Assist with ordering research consumables.
* Undertake literature searches and reviews.
* Assist with routine team administration.
* Assist with preparing reports, graphs, figures and presentations on research outcomes at different stages of the research cycle.
* Carry out any other duties as reasonably directed by your supervisor.
Qualifications
* Completion of a degree level qualification in Molecular Biology / Biochemistry / Pharmaceutical or completion of a Diploma with relevant work experience; or an equivalent combination of relevant experience and/or education/training.
* Excellent practical research skills and experience in molecular biology techniques, including PCR, primer design, nucleic acid extraction and purification, in‐vitro transcription (IVT).
* Experience using analytical techniques, including U.V spectroscopy, agarose gel electrophoresis, capillary GE and HPLC.
* Ability to work collaboratively with colleagues.
* Ability to work independently on routine procedures.
* Excellent oral and written communication skills.
* Well‐organised, methodical and self‐motivated.
* Previous experience in mRNA manufacturing in an industry setting would be considered favourably.
Employment and Legal Information

Applicants must maintain unrestricted work rights in Australia for the duration of this appointment. Pre‐employment checks may include verification of the right to work in Australia, qualifications and mandatory immunisations. Employer‐sponsored work rights are not available for this appointment.

Application Deadline

Applications close 18 June AEST.

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