* Blood cancer research at a world renowned medical research institute
* Dedicated role in an MRFF funded clinical study
* Attractive salary packaging & superannuation options
About QIMR Berghofer
QIMR Berghofer is a world-leading translational medical research institute focused on improving health by developing new diagnostics, better treatments and prevention strategies, specifically in the areas of Cancer, Infection and Inflammation, Brain and Mental Health, and Population Health. Based in Herston, Brisbane and working in close collaboration with clinicians and other research institutes, QIMR Berghofer is home to more than 600 scientists, students and non-research staff.
About The Leukaemia Research Lab
The Leukaemia Research Laboratory is dedicated to researching myeloid blood cancers such as acute myeloid leukaemia (AML), myelodysplastic syndrome (MDS) and the myeloproliferative neoplasms (MPN). The laboratory's efforts are concentrated on how the mutational composition of blood cancer driving stem cells determines disease progression and the response to treatment. To achieve this, research has focused on generating robust models of blood cancers and dissecting the pathways of self-renewal in blood cancer stem cells and normal blood stem cells. This work is complemented with the generation of single cell sequencing and spatial transcriptomics platforms for the analysis of primary patient samples. Findings are utilised to support investigator-initiated clinical trials for the treatment of myeloid blood cancers.
Role Purpose / Responsibilities
We are seeking a highly motivated bioinformatician to work together with all members of the group on an MRFF clinical observational study in MPN. The candidate should have a track record of outstanding achievement during their undergraduate and graduate studies with relevance to bioinformatics. As a member of the lab, you will be required to work independently and in collaboration with other team members to develop pipelines and analyse a number of data sets arising from this study.
* Planning, interpretation and communication of bioinformatics experiments
* Processing and analysis of short-read single cell cDNA Illumina sequencing data
* Processing and analysis of long-read sequencing data generated using Oxford Nanopore Technology
* Processing and analysis of spatial transcriptomics data generated e.g. using the Xenium platform
* Sourcing and integration of publicly available sequencing data
* Preparation of data and figures for papers
* Ongoing critical appraisal of current and emerging literature
* Education and teaching of junior lab members where relevant
About you
You are required to have:
* PhD qualification and previous experience in bioinformatics, computational biology, or a related field
* Proficient in a programming language like R or Python
* Familiar with Linux/command line environments
* Machine learning and statistics basics (classification, clustering, dimension reduction, differential gene expression)
* Experience in the majority of techniques outlined under primary responsibilities
* Capacity to contribute to several projects concurrently
* Demonstrated ability to maintain accurate and reliable scientific records
* Exceptional organisational skills, with the ability to prioritise and coordinate tasks to meet competing deadlines
* Demonstrated ability to use good judgement when working with minimal or no supervision
* Strong interpersonal and communication skills, with the ability to relate to staff across all levels of the organisation
* Professional manner and presentation
* Excellent attention to detail with a high level of accuracy
Remuneration
Salary range is $98,983 to $106,201 FTE per annum plus super and generous salary packaging. This role could be adapted to either a full time (1.0 FTE) or part-time (≥0.6 FTE) position, fixed term appointment for 12 months.
What we offer
* Salary Packaging
* State of the art facilities
* Stimulating work setting focussed on cutting edge medical research
* Supportive and collaborative team environment
Applicants must be an Australian Citizen, Permanent Resident or hold a valid work permit or visa. Work eligibility will be checked as part of the recruitment process.
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