Organisation/Company UNIVERSITY OF SYDNEY Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Established Researcher (R3) Country Australia Application Deadline 28 May 2025 - 00:00 (UTC) Type of Contract Other Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description
* Full-time position, fixed term until June 2028
* Exciting opportunity to work with Associate Professor Sudarshini Ramanathan at the ANZAC Research Institute
* Base Salary from level B - $122,830 - $145,858 + 17% superannuation
About the opportunity
The successful candidate will join the Translational Neuroimmunology group, led by Associate Professor Sudarshini Ramanathan. This research group is affiliated with Sydney Medical School, the Faculty of Medicine and Health, University of Sydney across the Kids Neuroscience Centre, Children's Hospital at Westmead and the ANZAC Research Institute, Concord Campus.
The successful candidate will be a lead scientist providing immunology and molecular biology expertise to a multidisciplinary team; and will take a key role in executing projects evaluating the immunobiology underlying autoimmune diseases of the nervous system. The candidate should have a strong background in immunology and molecular biology, with core competencies detailed below. Data generated from scientific experiments will be analysed in the context of clinical data, with a translational aspect to all research outputs from our group.
Research Responsibilities:
* design and execute laboratory experiments for specific research projects under the supervision of the Translational Neuroimmunology Group Head
* high competency in tissue culture based experiments using cell lines. This will involve maintenance of cell stocks, culturing of cells for transfection of expression constructs for downstream functional studies and protein analysis
* high competency in flow cytometry experiments and analysis
* high competency in microscopy
* high competency in molecular biology techniques including subcloning of DNA plasmids, sequencing, PCR and restriction enzyme digestions, and generation of monoclonal antibodies
* high competency in the analysis and graphing of research data (including expertise in GraphPad Prism, Adobe Illustrator, R studio etc)
* competency in lymphocyte culture
* competency in B cell immunology
* competency and experience of analysing single-cell datasets, including RNA-seq and immunoglobulin sequences is desirable
* competency in neuroscience including dissection for and propagation of murine neuronal cell cultures is desirable
* competency in performing and analysing tissue immunohistochemistry and immunoblotting is desirable
* planning and execution of biological sample preparation and storage, database construction and management
* identify and troubleshoot technical or scientific problems, working collaboratively with other scientists and clinicians as required
* provide assistance to on going study coordination under the supervision of the group Head
* this position requires meticulous care and handing of rare patient samples and the applicant must demonstrate a high level of responsibility and reliability
Training and Development
* present experimental results and work-in-progress in laboratory and institute meetings, as well as national and international conferences
* form the basis of existing and new collaborations with clinicians and scientists locally, nationally and internationally; with intellectual and practical input to projects
* contribute to the design, data acquisition and analysis, and writing of high-quality research project grants and research publications
* continuously improve scientific knowledge and technical skills
* train, mentor, and cosupervise new team members and students within the Translational Neuroimmunology Group
* ensure effective communication and liaison within the research program which includes the project team and collaborators, especially at the clinical- laboratory interface.
* conduct original research independently or as part of a team, focusing on publication, conference presentations, and securing research funding
* maintain a research profile, including publication of book chapters, peer-reviewed journal articles, conference and/or seminar papers
* develop research collaborations and engage in translational research that result in knowledge or technology transfer leading to commercialisation, improved policy or practice, or enhancement to industry, the profession or community
* maintain quality, standards and excellence in research activities and output
* provide informal mentoring and guidance to lower-level academics and supervise postgraduate research students or projects where appropriate
* undertake other duties appropriate within the classification level as required.
Administration
* assist with governance and ethics requirements
* participate in ordering consumables and other laboratory duties essential to the efficient running of the team, as requested by the group Head
* participate in weekly meetings with the group Head
* comply with OH&S requirements and other institutional policies
About you
* doctorate or PhD in a relevant field
* background in basic science research with a focus on autoimmune neurology
* proven experience in the development of live cell based assays, complement mediated cytotoxicity functional assays, cytokine and chemokine evaluation, and processing of peripheral blood mononuclear cells
* proven experience conducting original research and engaging in scholarly activity
* a developing network of academic, industry and professional partners and stakeholders
* proven experience supervising and mentoring others
* experience in teaching and learning, as evidenced by participation in team teaching and teaching in a variety of settings.
To keep our community safe, please be aware of our COVID safety precautions which form our conditions of entry for all staff, students and visitors coming to campus.
Pre-employment checks
Your employment is conditional upon the completion of all role required pre-employment or background checks in terms satisfactory to the University. Similarly, your ongoing employment is conditional upon the satisfactory maintenance of all relevant clearances and background check requirements. If you do not meet these conditions, the University may take any necessary step, including the termination of your employment.
Applications (including a cover letter, CV, and any additional supporting documentation) can be submitted via the Apply button at the top of the page.
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For a confidential discussion about the role, or if you require reasonable adjustment or any documents in alternate formats, please contact, Ajaypal Singh, Recruitment Operations by email to .
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