Together we are making a difference for kids living with genetic disease. Children's Medical Research Institute (CMRI) was Australia's first dedicated paediatric research facility and is now one of the nation's most highly regarded independent medical research centres. CMRI's research programs are supported by state‐of‐the‐art facilities and committed research and support staff. In a collaborative effort with the University of Sydney and the Sydney Children's Hospital Network (SCHN), CMRI has built a world‐leading gene therapy program, capturing the entire translational journey from idea to therapeutic reality, including clinical viral vector manufacturing facility. Aligned with our growing efforts in the gene therapy space, in 2016 CMRI has established Translational Vectorology Research Unit (TVRU), which specialises in the development and validation of novel recombinant adeno‐associated viral vectors (rAAV) and development and translation of individualised gene therapeutics for the treatment of rare paediatric genetic conditions. TVRU benefits from direct leadership of Prof. Lisowski, a world expert in the fields of vectorology and vector‐based gene therapies. In addition to highly dedicated and motivated researchers, our achievements are made possible by a loyal network of community supporters, highly engaged donors and the very successful Jeans for Genes fundraising campaign.
About the Role
Research Assistant – Translational Vectorology Research Unit (TVRU) Join a team advancing next‐generation gene delivery technologies. The Translational Vectorology Research Unit (TVRU) is seeking a motivated Research Assistant to support our work in viral vector design, production, and characterisation, as well as using those tools to develop therapeutic candidates for rare paediatric genetic disorders. This hands‐on role is ideal for someone who thrives in the lab, enjoys problem‐solving, and wants to contribute to impactful translational research. This is a 12‐month fixed‐term position, with potential for continuation based on performance and funding.
Responsibilities
* Design, clone, produce, purify, and test recombinant and replication‐competent viral vectors (AAV, LVV).
* Maintain and manipulate a range of mammalian cell types, including immortalised lines and pluripotent stem cells.
* Perform cell differentiation and characterisation under BSL2/2+ conditions.
* Work with primary human cells and tissues as required.
* Conduct routine molecular biology and QA/QC assays (PCR, qPCR, ddPCR, cloning, DNA purification, etc.).
* Undertake general laboratory duties, including equipment and reagent maintenance.
* Contribute to the preparation and updating of SOPs.
Qualifications
Bachelor of Science (or equivalent) with 2+ years' experience in molecular biology and mammalian cell culture.
Required Skills
* Strong attention to detail, excellent communication skills, and a willingness to learn new protocols and technologies.
* Hands‐on experience with viral vectors, mammalian cell culture, or stem cell culture (highly desirable).
* Experience with animal models is an advantage but not required.
* Proficiency with PC and Mac operating systems and Microsoft Office (especially Excel).
* Enthusiasm, motivation, and strong technical ability.
Preferred Skills
* None specified.
Benefits
* Supportive, flexible, and collaborative team environment.
* Opportunities to learn new techniques and grow your technical skillset.
Equal Opportunity Statement
We kindly request no unsolicited resumes or approaches from Recruitment Agencies. We will not be responsible for any fees related to unsolicited resumes. Children's Medical Research Institute is an equal‐opportunity employer. We are dedicated to attracting, retaining, and developing our people. We are an Equal Opportunity Employer, and we embrace diversity and inclusion, we strongly encourage applications from those who identify as being Aboriginal or Torres Strait Islander.
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