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Senior scientist ii / associate principal scientist – dmpk

ONE NUCLEUS
Posted: 6 June
Offer description

Working within our fully equipped research laboratories in Cambridge, our established group of scientists are world leaders in multiple hit-ID technologies and structure-based drug discovery. Our scientists develop and apply lead generation and structure-based methods to solve problems in drug discovery and have generated cell active compounds and development candidates against targets in multiple therapeutic areas including oncology, neurodegeneration, anti-infectives and inflammation.

The Role – Job summary

We are seeking a highly motivated and experienced Senior Scientist II / Associate Principal Scientist (dependent on experience) in DMPK to support our small molecule discovery programs. This is a lab-based, hands-on role covering the full spectrum of discovery DMPK, including in vitro ADME assays, metabolite identification (MetID), and the design, bioanalysis and interpretation of in vivo pharmacokinetic and pharmacodynamic (PK/PD) studies.

As part of an organisation of ~70 scientists, you will play a key role in generating high-quality experimental data and translating DMPK insights to guide compound optimisation and candidate selection. You will work closely on multiple projects with medicinal chemistry and biology teams both at Vernalis and with our collaborators, as well as manage and direct work carried out at external CROs.

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