Could you be our next Senior Director, Immunology and Translation? This hybrid position is located in our Waltham, MA or Melbourne, Australia offices, requiring onsite presence three days a week. You will report to the Research Therapeutic Area Lead, Immunology/Transplant and Vaccines.
Responsibilities
Scientific Leadership & Disease Area Expertise
* Serve as the primary scientific expert and internal champion for one or more immunology disease areas, including rheumatology, neuroimmunology, and rare dermatology.
* Translate deep mechanistic understanding of immune pathology into actionable therapeutic hypotheses and target identification strategies.
* Maintain a comprehensive view of the competitive landscape, emerging science, and unmet medical need across assigned disease areas.
* Represent CSL Behring at key scientific conferences, advisory boards, and KOL meetings; build and leverage a broad external network of thought leaders, clinical investigators, and academic collaborators.
* Drive end‐to‐end asset progression from ideation through first‐in‐disease designation, integrating scientific rationale, translational endpoints, patient population selection, and regulatory strategy.
* Lead or co‐lead target and asset evaluation activities including preclinical data package reviews, mechanism‐of‐action assessments, and translational feasibility analyses.
* Provide scientific input to IND‐enabling studies, proof‐of‐concept study designs, and Phase 1/1b protocol development.
* Collaborate with the discovery and translational teams to define disease‐relevant biomarkers, pharmacodynamic readouts, and patient stratification strategies for early clinical programs.
* Actively contribute to R&D programs as a subject‐matter expert and provide guidance for the clinical development pathway.
* Collaborate with the Research Therapeutic Area Lead, RPLs, and Immunology core team members to develop and maintain a best‐in‐class immunology portfolio.
Cross‐Functional Collaboration & Strategic Input
* Partner with Business Development to assess in‐licensing, partnering, and acquisition opportunities within the immunology space, providing scientific due diligence leadership.
* Contribute to Target Product Profiles (TPPs), integrated development plans, and portfolio reviews.
* Provide disease area expertise to regulatory submissions, clinical study reports, and scientific communications.
* Work collaboratively with Medical Affairs, Clinical Operations, and translational colleagues to align development strategies.
Qualifications
* MD, DO, or PhD in Immunology or a closely related discipline.
* 12+ years of experience in drug development within a biotech, pharmaceutical, or academic environment.
* Demonstrated experience in preclinical to first‐in‐disease (or equivalent early clinical milestone) in immunology.
* Deep scientific expertise in the immunological mechanisms underpinning autoimmune and inflammatory diseases.
* Established and active network in drug development with recognized relationships across rheumatology, neuroimmunology, and/or dermatology communities.
* Proven track record in evaluating preclinical and clinical assets, including target assessment, data package review, and go/no‐go decision‐making.
* Strong ability to synthesize complex scientific data and communicate strategy clearly to diverse audiences, including senior leadership.
The expected base salary range for this position is $302,000 – $350,000, with additional incentive compensation and equity available.
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